Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1768999 | 0.93 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTHPGDRECQL | |
| SCHEMBL10901608 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1TSHRHTTHPGDRECQL | |
| SCHEMBL8752326 | 0.73 | MAPT (0.50) | ALDH1A1TSHRHTTHPGDRECQL | |
| SCHEMBL8752329 | 0.72 | KDM4E (0.54) | ALDH1A1TSHRHTTHPGDPRKDC | |
| SCHEMBL31035280 | 0.72 | NPC1 (0.51) | ALDH1A1TSHRHTTHPGDPRKDC | |
| SCHEMBL17978292 | 0.69 | NPC1 (0.48) | ALDH1A1TSHRHTTHPGDRECQL | |
| SCHEMBL3512417 | 0.68 | HPGD (0.46) | ALDH1A1TSHRHTTHPGDPRKDC | |
| Dibenzofuran SCHEMBL27890395 | 0.68 | ALDH1A1 (0.59) | ALDH1A1TSHRHTTHPGDRECQL | |
| SCHEMBL31060240 | 0.67 | PRKDC (1.00) | ALDH1A1PRKDCGAAAGTR1 | |
| SCHEMBL31035740 | 0.67 | PRKDC (0.75) | ALDH1A1HTTHPGDPRKDCGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |