Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 2/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899401 | 0.88 | PLG (0.36) | PLGQDPRUSP7 | |
| SCHEMBL10900555 | 0.82 | PLG (0.35) | PLG | |
| SCHEMBL2721295 | 0.79 | HRH4 (0.40) | DRD4LSS | |
| SCHEMBL10899848 | 0.79 | HRH4 (0.40) | DRD4LSS | |
| SCHEMBL10902493 | 0.77 | CHRM2 (0.37) | PLGQDPRCCNT1CDK9 | |
| SCHEMBL10903297 | 0.77 | QDPR (0.36) | PLGQDPRCCNT1CDK9TSHR | |
| SCHEMBL10901823 | 0.76 | QDPR (0.43) | QDPR | |
| SCHEMBL10902920 | 0.73 | DRD2 (0.40) | HTR1F | |
| SCHEMBL10901399 | 0.73 | MEN1 (0.38) | PLGHTR1FQDPRDRD4LSS | |
| SCHEMBL10899853 | 0.73 | KDM4E (0.39) | PLGQDPRUSP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |