Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11223968

C=CCOC(=O)C(=CO)CC=C.N

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
TSHR P16473 2/20 0.34
MAPT P10636 2/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15234467 0.82 CYP3A4 (0.37) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL15234466 0.82 CYP3A4 (0.37) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL10901744 0.82 TSHR (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL11123344 0.80 NPSR1 (0.39) TSHRMAPTALDH1A1HSD17B10MEN1
SCHEMBL481459 0.80 MAPT (0.38) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL3902728 0.78 CYP3A4 (0.35) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL211113 0.78 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL2936820 0.78 MAPT (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL2938493 0.78 MAPT (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL2936821 0.78 MAPT (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4362528-A OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT SOCIETE ANONYME DITE: L'OREAL (FR) 1982-12-07 US disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed