Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28709915 | 0.97 | ALOX15 (0.46) | ALOX15PAOXGABRR1FFAR3LCK | |
| Bicarbonate SCHEMBL721165 | 0.83 | ALOX15 (0.42) | ALOX15PAOXGABRR1TSHRKMT2A | |
| Acetic Acid SCHEMBL1507470 | 0.81 | CA12 (0.56) | ALOX15PAOXFFAR3LCKFYN | |
| Acetic Acid SCHEMBL10939644 | 0.81 | CA12 (0.56) | ALOX15PAOXFFAR3LCKFYN | |
| Acetic Acid SCHEMBL5380789 | 0.79 | CA12 (0.53) | ALOX15PAOXTSHRKMT2ACA12 | |
| Trientine SCHEMBL9794969 | 0.79 | CA12 (0.58) | ALOX15PAOXTSHRKMT2ACA12 | |
| Acetic Acid SCHEMBL10476813 | 0.79 | CA12 (0.53) | ALOX15PAOXTSHRKMT2ACA12 | |
| Acetic Acid SCHEMBL2092025 | 0.79 | CA12 (0.53) | ALOX15PAOXTSHRKMT2ACA12 | |
| Acetic Acid SCHEMBL6580110 | 0.79 | CA12 (0.53) | ALOX15PAOXTSHRKMT2ACA12 | |
| Acetic Acid SCHEMBL28070853 | 0.79 | PAOX (0.38) | ALOX15PAOXGABRR1FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623616-A | DIFFUSIONPROOF COUPLER, TRIAZINE HARDENING AGENT | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-11-18 | — | — | US | disclosed |
| US-4010035-A | DEVELOPMENT INHIBITOR RELEASING COMPOUND, HARDENER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-03-01 | — | — | US | disclosed |