Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28709915 | 0.86 | ALOX15 (0.46) | ALOX15CA12CA6CA7CA9 | |
| Acetic Acid SCHEMBL10901752 | 0.83 | ALOX15 (0.44) | ALOX15CA12CA6CA7CA9 | |
| SCHEMBL466511 | 0.80 | — | — | |
| Bromide SCHEMBL31050231 | 0.77 | — | — | |
| Hydrogen Sulfide SCHEMBL10900451 | 0.77 | — | — | |
| Ethylenediamine SCHEMBL28594538 | 0.77 | — | — | |
| Ethylenediamine SCHEMBL8121893 | 0.77 | CA12 (0.47) | ALOX15CA12CA6CA7CA9 | |
| Sulfuric Acid SCHEMBL25412843 | 0.77 | LMNA (0.45) | ALOX15CA12CA6CA7CA9 | |
| Phosphoric Acid SCHEMBL8502119 | 0.77 | ANPEP (0.43) | ALOX15CA12CA6CA7CA9 | |
| Bicarbonate SCHEMBL2443699 | 0.75 | CA12 (0.67) | ALOX15CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436059-B2 | Aqueous floor polishing composition | OMNOVA SOLUTIONS INC. (US) | 2013-05-07 | — | — | US | claimed |
| US-20120130003-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. | 2012-05-24 | — | — | US | claimed |
| US-8124225-B2 | Aqueous floor polishing composition | OMNOVA SOLUTIONS INC. (US) | 2012-02-28 | — | — | US | claimed |
| US-20090324936-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. | 2009-12-31 | — | — | US | claimed |
| EP-2044161-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | Omnova Soltions Inc (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2008011020-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. (US) | 2008-01-24 | — | — | WO | claimed |
| CN-110655871-A | Polymer composition containing silane groups and coatings containing the same | 欧美诺华解决方案公司 | 2020-01-07 | — | — | CN | disclosed |
| US-10259928-B2 | Silane group-containing polymer composition and coatings containing same | OMNOVA SOLUTIONS INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-10253202-B2 | Protective coating compositions | OMNOVA SOLUTIONS INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170226368-A9 | PROTECTIVE COATING COMPOSITIONS | SYNTHOMER INC. | 2017-08-10 | — | — | US | disclosed |
| US-20160185997-A1 | PROTECTIVE COATING COMPOSITIONS | GLAS TRUST CORPORATION LIMITED, AS SECURITY AGENT (GB) | 2016-06-30 | — | — | US | disclosed |
| US-8940826-B2 | Protective coating compositions | OMNOVA SOLUTIONS INC. (US) | 2015-01-27 | — | — | US | disclosed |
| EP-2807223-A2 | SILANE GROUP-CONTAINING POLYMER COMPOSITION AND COATINGS CONTAINING SAME | Omnova Solutions Inc (US) | 2014-12-03 | — | — | EP | disclosed |
| US-20120130003-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. | 2012-05-24 | — | — | US | disclosed |
| US-8124225-B2 | Aqueous floor polishing composition | OMNOVA SOLUTIONS INC. (US) | 2012-02-28 | — | — | US | disclosed |
| WO-2011008631-A2 | PROTECTIVE COATING COMPOSITIONS | OMNOVA SOLUTIONS INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20090324936-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. | 2009-12-31 | — | — | US | disclosed |
| EP-2044161-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | Omnova Soltions Inc (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011020-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | OMNOVA SOLUTIONS INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2001007529-A1 | AQUEOUS FLOOR POLISHING COMPOSITION | S.C. JOHNSON COMMERCIAL MARKETS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |