Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901999 | 1.00 | NR3C1 (0.66) | NR3C1CYP19A1ARPGRNR3C2 | |
| Anecortave Acetate SCHEMBL8470303 | 0.80 | NR3C1 (1.00) | NR3C1CYP19A1ARPGRFNTA | |
| Anecortave Acetate SCHEMBL94110 | 0.80 | NR3C1 (1.00) | NR3C1CYP19A1ARPGRFNTA | |
| Anecortave Acetate SCHEMBL14612532 | 0.80 | NR3C1 (1.00) | NR3C1CYP19A1ARPGRFNTA | |
| Anecortave Acetate SCHEMBL2118233 | 0.80 | NR3C1 (1.00) | NR3C1CYP19A1ARPGRFNTA | |
| SCHEMBL16379536 | 0.79 | NR3C1 (0.81) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623172 | 0.79 | NR3C1 (0.53) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9241562 | 0.79 | NR3C1 (0.53) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623638 | 0.78 | NR3C1 (0.53) | NR3C1CYP19A1ARPGRNR3C2 | |
| SCHEMBL9623805 | 0.78 | NR3C1 (0.60) | NR3C1CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600538-A | Corticosteroids from 17-keto steroids via 20-cyano-Δ17 (20)-pregnanes | THE UPJOHN COMPANY (US) | 1986-07-15 | — | — | US | claimed |