Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899410 | 0.87 | NPC1 (0.40) | RAB9ANPC1LMNAMAPK13MAPK12 | |
| SCHEMBL10902026 | 0.76 | MKNK2 (0.43) | RAB9ANPC1LMNAMAPK13MAPK12 | |
| SCHEMBL10899375 | 0.76 | KMT2A (0.43) | RAB9ANPC1LMNAMAPK13MAPK12 | |
| SCHEMBL10901540 | 0.76 | NPC1 (0.40) | RAB9ANPC1LMNAMAPK13MAPK12 | |
| SCHEMBL10901636 | 0.76 | MKNK2 (0.47) | RAB9ANPC1LMNAMAPK14KMT2A | |
| SCHEMBL10903355 | 0.74 | PDGFRB (0.47) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL10902490 | 0.70 | KMT2A (0.43) | RAB9ANPC1LMNAMAPK14KMT2A | |
| SCHEMBL10899791 | 0.70 | MAPK14 (0.45) | MAPK13MAPK12MAPK11MAPK14GAA | |
| SCHEMBL10899817 | 0.70 | PDGFRB (0.48) | RAB9ANPC1MAPK14MAPTCYP1A2 | |
| SCHEMBL10901637 | 0.70 | PDGFRB (0.48) | RAB9ANPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |