Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645412 | 0.89 | TTR (0.65) | TTRLTA4HNR1H2BAXCAMK2A | |
| SCHEMBL396882 | 0.86 | ALDH1A1 (0.52) | TTRLTA4HNR1H2BAXLMNA | |
| SCHEMBL5401074 | 0.80 | MEN1 (0.54) | LTA4HNR1H2BAXLMNAMAPT | |
| SCHEMBL4958922 | 0.78 | TTR (0.65) | TTRLTA4HNR1H2BAXMEN1 | |
| SCHEMBL676467 | 0.78 | MEN1 (0.56) | TTRLTA4HNR1H2BAXMEN1 | |
| SCHEMBL29449754 | 0.78 | TTR (0.57) | TTRLTA4HNR1H2BAXLMNA | |
| SCHEMBL260447 | 0.78 | TTR (0.57) | TTRLTA4HNR1H2BAXLMNA | |
| SCHEMBL2916124 | 0.78 | LTA4H (0.52) | TTRLTA4HNR1H2BAXLMNA | |
| SCHEMBL19661665 | 0.78 | TTR (0.44) | TTRLTA4HNR1H2BAXCAMK2A | |
| SCHEMBL9588301 | 0.77 | TTR (0.53) | TTRLTA4HNR1H2BAXMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575385-A | POLYSULFONES CONTACTED WITH BENZENE COMPOUND | MONSANTO COMPANY (US) | 1986-03-11 | — | — | US | disclosed |