Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902153 | 1.00 | GPR183 (0.55) | GPR183GAAKMT2AMEN1KCNJ1 | |
| SCHEMBL10901880 | 0.89 | GPR183 (0.56) | GPR183GAAKMT2AMEN1EBP | |
| SCHEMBL10901877 | 0.89 | GPR183 (0.56) | GPR183GAAKMT2AMEN1EBP | |
| SCHEMBL10900513 | 0.86 | EBP (0.73) | GAAKMT2AMEN1KCNJ1KCNH2 | |
| SCHEMBL10900512 | 0.86 | EBP (0.73) | GAAKMT2AMEN1KCNJ1KCNH2 | |
| SCHEMBL10900566 | 0.85 | EBP (0.72) | GPR183GAAKMT2AMEN1EBP | |
| SCHEMBL10900561 | 0.85 | EBP (0.72) | GPR183GAAKMT2AMEN1EBP | |
| SCHEMBL10900781 | 0.84 | KCNJ1 (0.59) | KMT2AMEN1KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL10899492 | 0.84 | THRB (0.65) | GPR183KMT2AMEN1KCNJ1KCNH2 | |
| SCHEMBL10897540 | 0.83 | ACHE (0.59) | GPR183GAAKMT2AMEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |