SCHEMBL10902205

SCHEMBL10902205

CCCCC[C@H]1CC[C@H](CCc2ccc(-c3ccc(CC[C@H]4CC[C@H](CCCC)CC4)cc3)cc2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HRH3 Q9Y5N1 3/20 0.43
RARB P10826 6/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 1/20 0.42
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RARA P10276 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
SPHK1 Q9NYA1 1/20 0.40
HRH4 Q9H3N8 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902212 1.00 GPR84 (0.44) GPR84MAOAMAOBHRH3RARB
SCHEMBL10789712 0.98 MAOA (0.44) GPR84MAOAMAOBHRH3RARB
SCHEMBL10789703 0.98 MAOA (0.44) GPR84MAOAMAOBHRH3RARB
SCHEMBL10903179 0.95 MAOA (0.42) GPR84MAOAMAOBHRH3RARB
SCHEMBL10903184 0.95 MAOA (0.42) GPR84MAOAMAOBHRH3RARB
SCHEMBL10792048 0.95 HRH3 (0.49) GPR84HRH3RARBTSHRHSD17B10
SCHEMBL11058303 0.95 HRH3 (0.49) HRH3RARBTSHRHSD17B10MAPT
SCHEMBL11058295 0.95 HRH3 (0.49) HRH3RARBTSHRHSD17B10MAPT
SCHEMBL10899257 0.95 RARB (0.46) GPR84MAOAMAOBHRH3RARB
SCHEMBL11061549 0.95 MAOA (0.49) GPR84MAOAMAOBHRH3RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4583826-A Phenylethanes HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US disclosed