Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902617 | 0.87 | TP53 (0.48) | TP53TDP1CA12CA1CA2 | |
| SCHEMBL10900315 | 0.81 | MMP2 (0.36) | TP53TDP1CA12CA1CA2 | |
| SCHEMBL9684530 | 0.80 | MEN1 (0.47) | TP53TDP1CA12CA1CA2 | |
| SCHEMBL10903137 | 0.78 | — | — | |
| SCHEMBL11082215 | 0.77 | TSHR (0.39) | TP53TDP1CA12CA1CA2 | |
| SCHEMBL10902864 | 0.75 | TP53 (0.34) | TP53TDP1TSHRCYP3A4LPAR3 | |
| SCHEMBL10874480 | 0.75 | — | — | |
| SCHEMBL10903141 | 0.72 | TP53 (0.36) | TP53TDP1CA12CA1CA2 | |
| SCHEMBL474087 | 0.72 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11271484 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608367-A | γ-Pyrone phosphoric ester derivatives and insecticidal and miticidal compositions thereof | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-08-26 | — | — | US | disclosed |