Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903054 | 0.87 | TP53 (0.37) | TP53TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL10902272 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL10900218 | 0.78 | — | — | |
| SCHEMBL10902810 | 0.75 | TP53 (0.44) | TP53TDP1LPAR2LPAR3TSHR | |
| SCHEMBL11800843 | 0.75 | LPAR3 (0.41) | LPAR2LPAR3 | |
| SCHEMBL7772192 | 0.75 | — | — | |
| SCHEMBL11082217 | 0.73 | MMP1 (0.35) | LPAR2LPAR3TSHR | |
| SCHEMBL9684530 | 0.71 | MEN1 (0.47) | TP53TDP1LPAR2LPAR3TSHR | |
| SCHEMBL11271487 | 0.71 | — | — | |
| SCHEMBL10904374 | 0.71 | TP53 (0.34) | TP53TDP1ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608367-A | γ-Pyrone phosphoric ester derivatives and insecticidal and miticidal compositions thereof | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-08-26 | — | — | US | disclosed |
| US-4320126-A | INSECTICIDES, MITICIDES, NEMATOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-16 | — | — | US | disclosed |
| US-4308258-A | Pyrimidin-4-yl-phosphorus esters and insecticidal, acaricidal or nematocidal compositions and methods using them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-12-29 | — | — | US | disclosed |