SCHEMBL10902876

SCHEMBL10902876

CS(=O)(=O)c1ccc(NN/C(=N\c2ccccc2)Nc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.50
CRHR1 P34998 1/20 0.47
MGLL Q99685 4/20 0.46
FAAH O00519 3/20 0.46
IDO1 P14902 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 1/20 0.43
CA9 Q16790 1/20 0.43
TGM2 P21980 1/20 0.41
BCAT2 O15382 1/20 0.40
CA7 P43166 1/20 0.40
F2 P00734 1/20 0.40
PRKDC P78527 1/20 0.40
ATR Q13535 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
LMNA P02545 1/20 0.40
CYP2D6 P10635 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902879 1.00 PTGS2 (0.50) PTGS2CRHR1MGLLFAAHIDO1
SCHEMBL4100165 0.84 TDP1 (0.53) PTGS2CRHR1F2GRIN2DGRIN3B
SCHEMBL10901551 0.84 TDP1 (0.53) PTGS2CRHR1F2GRIN2DGRIN3B
SCHEMBL10902928 0.81 CRHR1 (0.49) PTGS2CRHR1F2GRIN2DGRIN3B
SCHEMBL10902931 0.81 CRHR1 (0.49) PTGS2CRHR1F2GRIN2DGRIN3B
SCHEMBL6154347 0.75 KMT2A (0.59) CRHR1CA1CA2CA4CA9
SCHEMBL10903350 0.74 SMN1; SMN2 (0.60) CA9LMNACYP2D6KMT2A
SCHEMBL10903357 0.74 SMN1; SMN2 (0.60) CA9LMNACYP2D6KMT2A
SCHEMBL14534719 0.73 PTGS2 (0.64) PTGS2MGLLFAAHIDO1CA1
SCHEMBL9913187 0.73 PTGS2 (0.72) PTGS2MGLLFAAHCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4615970-A TRIAZOLE ANTIFOGGING COMPOUNDS AND SALTS PLUS POLYOXYETHYLENE GLYOL DERIVATIVES; QUICK PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1986-10-07 US disclosed