SCHEMBL109034

SCHEMBL109034

C=Cc1ccc(Cl)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.60
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.48
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
MAPT P10636 2/20 0.46
GABRA1 P14867 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
AMY1A P0DUB6 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376510 1.00 TDP1 (0.60) TDP1ALDH1A1TP53GRIN2DGRIN3B
Hydrogen Sulfide SCHEMBL29194425 0.98 TDP1 (0.58) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL11784870 0.89 TDP1 (0.50) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL17353953 0.86 ALDH1A1 (0.50) TDP1ALDH1A1TP53GRIN2DGRIN3B
Styrene SCHEMBL9066030 0.86 ALDH1A1 (0.52) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL28422184 0.82 TDP1 (0.44) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL9729264 0.81 TDP1 (0.56) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL820295 0.80 ALDH1A1 (0.52) TDP1ALDH1A1TP53TSHRHSD17B10
SCHEMBL7831326 0.80 TDP1 (0.60) TDP1ALDH1A1TP53GRIN2DGRIN3B
SCHEMBL29556567 0.80 ALDH1A1 (0.52) TDP1ALDH1A1TP53TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6256 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-20250345406-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS INC (US) 2025-11-13 US claimed
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-10-23 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
EP-3902854-B1 POLYMERIC COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER WITH BUTADIENE AND STYRENE BLOCKS AND A COMPATIBLE PLASTICISER MICHELIN & CIE (FR) 2025-10-15 EP claimed
US-12428552-B2 Polymeric composition comprising a thermoplastic elastomer with butadiene and styrene blocks and a compatible plasticizer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-09-30 US claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 WO claimed
EP-3647333-B1 CURABLE PETROLEUM RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF KOLON INC (KR) 2025-06-18 EP claimed
US-20250188013-A1 LIPID COMPOUND AND USE THEREOF THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-06-12 US claimed
EP-0017939-B1 METHOD FOR PRODUCING MODIFIED POLYPHENYLENE OXIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-20 EP claimed
EP-0052854-A1 Polyphenylene oxide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-02 EP claimed
US-4283511-A GRAFT POLYMERIZATION WITH A STYRENE MONOMER AND A POLAR VINYL MONOMOER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-11 US claimed
EP-0017939-A1 Method for producing modified polyphenylene oxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-10-29 EP claimed
US-4201702-A Process to produce allyl halides copolymers BLOUNT DAVID H 1980-05-06 US claimed
US-4173593-A Metal acetylacetonate latent accelerators for an epoxy-styrene resin system WESTINGHOUSE ELECTRIC CORP. (US) 1979-11-06 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed
US-4049590-A MIXING POLYOL- POLYETHERS OR POLYESTERS WITH A CROSSLINKED ADDITION POLYMER AND A CROSSLINKING AGENT, THEN REACTING WITH A POLYISOCYANATE BASF AKTIENGESELLSCHAFT (DT) 1977-09-20 US claimed
US-4029616-A Polymer composition of ethylenic compounds and pullulan SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed
US-3954724-A ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US claimed