Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955750 | 0.82 | TP53 (0.44) | TDP1TSHRHSD17B10TP53GRIN2D | |
| SCHEMBL29376510 | 0.81 | TDP1 (0.60) | TDP1TSHRHSD17B10TP53GRIN2D | |
| SCHEMBL109034 | 0.81 | TDP1 (0.60) | TDP1TSHRHSD17B10TP53GRIN2D | |
| Hydrogen Sulfide SCHEMBL29194425 | 0.79 | TDP1 (0.58) | TDP1TSHRHSD17B10TP53GRIN2D | |
| SCHEMBL7831326 | 0.76 | TDP1 (0.60) | TDP1TSHRHSD17B10TP53GRIN2D | |
| SCHEMBL2097650 | 0.75 | TDP1 (0.65) | TDP1TSHRHSD17B10TP53GRIN2D | |
| SCHEMBL1689790 | 0.74 | TDP1 (0.58) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1689789 | 0.74 | TDP1 (0.58) | TDP1TP53GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6582916 | 0.74 | CYP3A4 (0.43) | TDP1TP53MAPTALDH1A1GAA | |
| SCHEMBL8580636 | 0.73 | TDP1 (0.62) | TDP1TSHRHSD17B10TP53GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171354-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |