SCHEMBL10903444

SCHEMBL10903444

CC(C)(Cl)c1cc(Cc2ccccc2)c(O)c(Cc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
BCL2L1 Q07817 1/20 0.48
PTPN1 P18031 3/20 0.45
PTPN2 P17706 1/20 0.45
PTPN6 P29350 1/20 0.45
MEN1 O00255 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
KMT2A Q03164 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ALOX5 P09917 1/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10871265 0.86 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10907301 0.86 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10906201 0.84 BCL2 (0.50) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11212329 0.84 BCL2 (0.50) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10904873 0.78 BCL2 (0.47) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL12922969 0.78 ESR1 (0.43) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10906410 0.78 PTPN1 (0.44) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL18055780 0.78 ALDH1A1 (0.43) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL7110304 0.77 CYP2C9 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9790296 0.76 HSD17B10 (0.67) BCL2BCL2L1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4613642-A ANTIOXIDANTS FOR POLYOLEFINS ETHYL CORPORATION (US) 1986-09-23 US disclosed