Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 6/20 | 0.50 |
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL10945586 | 0.93 | CES2 (0.50) | TSHRDAONAPRTCES2CES1 | |
| Tetrapropylammonium SCHEMBL104199 | 0.91 | ALDH1A1 (0.56) | TSHRSRD5A2ALDH1A1TP53RARB | |
| Tetrapropylammonium SCHEMBL11370615 | 0.91 | ALDH1A1 (0.56) | TSHRSRD5A2ALDH1A1TP53RARB | |
| Tetrabuthylammonium SCHEMBL23045181 | 0.88 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Tetrapropylammonium SCHEMBL104867 | 0.88 | KMT2A (0.53) | TP53 | |
| Tetrabuthylammonium SCHEMBL108879 | 0.88 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Tetrapentylammonium SCHEMBL10947994 | 0.88 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Tetrahexylammonium SCHEMBL868317 | 0.86 | CES2 (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9792086 | 0.86 | CES2 (0.54) | TSHRDAONAPRTCES2CES1 | |
| Tetrabuthylammonium SCHEMBL28609595 | 0.86 | TSHR (0.52) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108148394-B | Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom | 赢创运营有限公司 | 2021-12-28 | — | — | CN | claimed |
| EP-3330311-B1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10633519-B2 | Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components | EVONIK OPERATIONS GMBH (DE) | 2020-04-28 | — | — | US | claimed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | claimed |
| US-20180155515-A1 | STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM | EVONIK OPERATIONS GMBH (DE) | 2018-06-07 | — | — | US | claimed |
| EP-2641924-B1 | Non-aqueous coating agent which hardens at room temperature | EVONIK DEGUSSA GMBH (DE) | 2018-05-02 | — | — | EP | claimed |
| EP-2641925-B1 | Adducts from isocyanatoalkyl trialkoxysilanes and aliphatic, alkyl-branched diols or polyols | EVONIK DEGUSSA GMBH (DE) | 2017-02-01 | — | — | EP | claimed |
| EP-2411439-B1 | PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE | EVONIK DEGUSSA GMBH (DE) | 2016-11-16 | — | — | EP | claimed |
| EP-1475399-B1 | Solid polyurethane powder coatings compositions containing uretdione groups and curable at low temperature | EVONIK DEGUSSA GMBH (DE) | 2016-08-03 | — | — | EP | claimed |
| US-9266825-B2 | Copolymers of isocyanatoalkyltrialkoxysilanes and urethanediols | EVONIK DEGUSSA GMBH (DE) | 2016-02-23 | — | — | US | claimed |
| US-20080265201-A1 | LOW-TEMPERATURE-CURABLE POLYURETHANE COMPOSITIONS WITH URETDIONE GROUPS, CONTAINING POLYMERS BASED ON POLYOLS THAT CARRY SECONDARY OH GROUPS | DEGUSSA GMBH (DE) | 2008-10-30 | — | — | US | claimed |
| US-20080214728-A1 | One-Component Polyurethane Systems that are Devoid of Metal | EVONIK DEGUSSA GMBH (DE) | 2008-09-04 | — | — | US | claimed |
| US-20080139753-A1 | Highly Reactive Uretdione Group-Containing Polyurethane Compositions Based on 1,4-Diisocyanato-Dicyclohexyl Methane | DEGUSSA GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| US-20080097025-A1 | Highly Reactive Polyurethane Compositions Containing Uretdione Groups | DEGUSSA GMBH (DE) | 2008-04-24 | — | — | US | claimed |
| US-7307135-B2 | High-reactivity liquid polyurethane systems which contain uretdione groups and can be cured at a low temperature | DEGUSSA AG (DE) | 2007-12-11 | — | — | US | claimed |
| US-20070282089-A1 | Method for producing solid highly-reactive polyurethane compositions containing uretdione groups | DEGUSSA AG (DE) | 2007-12-06 | — | — | US | claimed |
| US-20050239956-A1 | Polyurethane composition which contains an uretdione group | DEGUSSA AG (DE) | 2005-10-27 | — | — | US | claimed |
| US-20050096451-A1 | High-reactivity liquid polyurethane systems which contain uretdione groups and can be cured at a low temperature | DEGUSSA AG (DE) | 2005-05-05 | — | — | US | claimed |
| US-20050096450-A1 | Low temperature curable polyurethane compositions containing uretdione groups | DEGUSSA AG (DE) | 2005-05-05 | — | — | US | claimed |
| US-4522729-A | CXONTACTING IMPORITIES WITH TETRAALKYLAMMONIUM SALT | PHILLIPS PETROLEUM COMPANY (US) | 1985-06-11 | — | — | US | claimed |