Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012568 | 0.78 | IDO1 (0.45) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL2012572 | 0.78 | IDO1 (0.45) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL10904387 | 0.77 | IDO1 (0.47) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL430935 | 0.76 | IDO1 (0.68) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL7514298 | 0.76 | IDO1 (0.68) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL430934 | 0.76 | IDO1 (0.68) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL8621304 | 0.76 | IDO1 (0.53) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL10902980 | 0.76 | TBXAS1 (0.41) | IDO1PAMKMT2A | |
| SCHEMBL1158309 | 0.73 | IDO1 (0.59) | IDO1PAMHTR2ASIGMAR1HTR2C | |
| SCHEMBL194630 | 0.73 | IDO1 (0.59) | IDO1PAMHTR2ASIGMAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564476-A | Aryl fatty acid leukotriene synthesis inhibitors | MCNEILAB, INC. (US) | 1986-01-14 | — | — | US | disclosed |