Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146486 | 0.83 | CYP2C19 (0.63) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL17015173 | 0.82 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL16317067 | 0.82 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2619217 | 0.80 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2610980 | 0.80 | CYP2C19 (0.61) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL22202124 | 0.80 | KDM4E (0.58) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11666576 | 0.79 | CYP2C19 (0.59) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2282918 | 0.78 | SMN1; SMN2 (0.67) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10925804 | 0.78 | ALDH1A1 (0.66) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL17996453 | 0.77 | KMT2A (1.00) | CYP2C19SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578514-A | Synthesis of sulfilimines | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | disclosed |