Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL7060116 | 0.92 | KMT2A (0.65) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11666576 | 0.83 | CYP2C19 (0.59) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10904698 | 0.83 | CYP2C19 (0.69) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2282918 | 0.78 | SMN1; SMN2 (0.67) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17015173 | 0.78 | CYP2C19 (1.00) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10925804 | 0.78 | ALDH1A1 (0.66) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16317067 | 0.78 | CYP2C19 (1.00) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3612079 | 0.77 | KDM4E (0.55) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5138891 | 0.77 | F2 (0.59) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2619217 | 0.76 | CYP2C19 (0.61) | CYP2C19ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516532-A2 | POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES | Dickmeis, Marcus (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011085793-A2 | POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES | DICKMEIS MARCUS (DE) | 2011-07-21 | — | — | WO | disclosed |