Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906861 | 1.00 | CTBP2 (0.47) | CTBP2CES1CES2AKR1B1CA12 | |
| SCHEMBL9748148 | 0.79 | CTBP2 (0.47) | CTBP2CES1CES2AKR1B1TSHR | |
| SCHEMBL9748142 | 0.79 | CTBP2 (0.47) | CTBP2CES1CES2AKR1B1TSHR | |
| SCHEMBL1346095 | 0.77 | TSHR (0.56) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL27520004 | 0.74 | TSHR (0.53) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL28515878 | 0.74 | CES1 (0.47) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL7278868 | 0.74 | CES1 (0.57) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL29185461 | 0.73 | CA12 (0.41) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL5089657 | 0.71 | CA12 (0.47) | CES1CES2AKR1B1CA12CA1 | |
| SCHEMBL4976027 | 0.71 | CES1 (0.44) | CES1CES2AKR1B1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614813-A | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0158153-A2 | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1985-10-16 | — | — | EP | disclosed |