SCHEMBL9748142

SCHEMBL9748142

CO/C(Cc1ccccc1)=N\O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
RAB9A P51151 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 3/20 0.42
ALDH1A1 P00352 4/20 0.42
LMNA P02545 3/20 0.42
KDM4E B2RXH2 2/20 0.42
USP2 O75604 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
AKR1B1 P15121 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
TSHR P16473 1/20 0.40
MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9748148 1.00 CTBP2 (0.47) CTBP2L3MBTL1RAB9AMEN1KMT2A
SCHEMBL10906367 0.79 CTBP2 (0.47) CTBP2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL10906861 0.79 CTBP2 (0.47) CTBP2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL28108264 0.73 ALDH1A1 (0.66) KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL6295378 0.73 CES2 (0.48) L3MBTL1RAB9AMEN1KMT2ANPC1
SCHEMBL2154441 0.73 CES1 (0.48) L3MBTL1RAB9AMEN1KMT2ANPC1
SCHEMBL2700591 0.71 CES2 (0.46) L3MBTL1RAB9AMEN1KMT2ANPC1
SCHEMBL3658960 0.71 CTBP2 (0.52) CTBP2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL10177334 0.71 CTBP2 (0.52) CTBP2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL14667472 0.71 CTBP2 (0.52) CTBP2L3MBTL1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0334863-B1 PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES AlliedSignal Inc. (US) 1992-04-15 EP disclosed
EP-0334863-A1 PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES. ALLIED CORP (US) 1989-10-04 EP disclosed
WO-1988004291-A1 PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES ALLIED CORPORATION (US) 1988-06-16 WO disclosed
US-4743701-A Process for the preparation of organo N-hydroxyimidates ALLIED CORPORATION (US) 1988-05-10 US disclosed