SCHEMBL10906472

SCHEMBL10906472

O=C=NCc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.63
ESR1 P03372 3/20 0.44
ESR2 Q92731 2/20 0.44
MIF P14174 2/20 0.44
CA2 P00918 4/20 0.41
CAMK2A Q9UQM7 1/20 0.41
ABAT P80404 1/20 0.41
CTBP2 P56545 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTR3A P46098 1/20 0.38
BACE1 P56817 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
IDO1 P14902 1/20 0.38
FNTA P49354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21089 0.88 MIF (0.44) TRPA1MIFALDH1A1
SCHEMBL22471901 0.85 MIF (0.43) TRPA1MIFALDH1A1
Water SCHEMBL14972874 0.85 MIF (0.43) TRPA1MIFALDH1A1
Water SCHEMBL29040332 0.85 MIF (0.43) TRPA1MIFALDH1A1
SCHEMBL19833054 0.82 TRPA1 (0.42) TRPA1MIFCA2ALDH1A1
SCHEMBL5466297 0.81 CYP3A4 (0.54) TRPA1ESR1ESR2MIFKDM4E
Cyclohexane SCHEMBL28302863 0.81 MIF (0.40) TRPA1MIFALDH1A1
SCHEMBL31094964 0.81 MIF (0.40) TRPA1MIFALDH1A1
SCHEMBL24833766 0.79 MIF (0.39) TRPA1MIFALDH1A1
SCHEMBL436823 0.79 IDO1 (0.42) TRPA1MIFCA2CTBP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116239756-A Polyisocyanate composition stable in visible light and application thereof 万华化学集团股份有限公司 2023-06-09 CN claimed
CN-116239756-A Polyisocyanate composition stable in visible light and application thereof 万华化学集团股份有限公司 2023-06-09 CN disclosed
CN-116239756-A Polyisocyanate composition stable in visible light and application thereof 万华化学集团股份有限公司 2023-06-09 CN disclosed
EP-0060673-B1 EXTRUDABLE FILM-FORMING COMPOSITIONS OF ZIEGLER-NATTA CATALYZED OLEFIN POLYMERS INCLUDING ANTI-GEL AND ANTI-BLOCK COMPONENTS UNION CARBIDE CORPORATION (US) 1986-03-05 EP disclosed