Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8196816 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL35119 | 0.91 | — | — | |
| Chloroform SCHEMBL7768433 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8192102 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8927139 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL2819782 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL7542885 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8927142 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL7542887 | 0.91 | TSHR (0.60) | — | |
| Chloroform SCHEMBL2118727 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4591551-A | ENZYMATIC TRANSMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1986-05-27 | — | — | US | disclosed |