Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8192102 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8927142 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8196816 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL7542885 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL7542887 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL7768433 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL8927139 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL2819782 | 1.00 | TSHR (0.60) | — | |
| Chloroform SCHEMBL2118727 | 0.95 | — | — | |
| Chloroform SCHEMBL6974119 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4688 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119971126-A | Medical collagen liquid for wound repair and preparation process thereof | 金华市景迪医疗用品有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119881172-A | Method for detecting olmesartan medoxomil bulk drug and genotoxic impurities | 中节能万润股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119745837-A | Preparation method of policosanol nanoparticle quick-release capsule | 湖北中古生物制药有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119607227-A | Nanometer material suitable for multi-mode diagnosis imaging and targeted photodynamic and photothermal cancer therapy, preparation and application | 中山大学附属第一医院 | 2025-03-14 | — | — | CN | claimed |
| CN-114644650-B | Method for extracting high-purity sphingomyelin from yolk powder | 广州白云山汉方现代药业有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-118359993-B | High-conductivity silver-copper alloy material and preparation process thereof | 泰州泰锦合金材料有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118425401-A | Thin-layer identification method of Chuantong cortex different-base original prescription particles | 四川新绿色药业科技发展有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118359993-A | High-conductivity silver-copper alloy material and preparation process thereof | 泰州泰锦合金材料有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118308339-A | Method for simultaneously purifying CA, SOD, CAT enzyme from animal erythrocytes | 云锦华彰(珠海)生物科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118286202-A | Ocean polysaccharide-based double-targeting double-nutrient carrier particle and preparation method and application thereof | 江苏蓝果临床营养科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| EP-0087993-B1 | PULVERIZED MIXTURE OF LIPID AND HYDROPHOBIC CONSTITUENTS, PROCESS FOR PREPARING THEM, HYDRATED LIPID LAMELLAR PHASES AND PROCESS FOR PREPARING THEM, PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING HYDRATED LAMELLAR LIPID PHASES | PARFUMS CHRISTIAN DIOR (FR) | 1986-07-02 | — | — | EP | claimed |
| EP-0182869-A1 | UTILIZING A HALOHYDROCARBON CONTAINING DISSOLVED WATER TO INACTIVATE A LIPID VIRUS | PURCELL, Robert H. (US) | 1986-06-04 | — | — | EP | claimed |
| EP-0170642-A2 | Liposomes containing steroid esters | Aktiebolaget Draco (SE) | 1986-02-05 | — | — | EP | claimed |
| WO-1985005273-A1 | UTILIZING A HALOHYDROCARBON CONTAINING DISSOLVED WATER TO INACTIVATE A LIPID VIRUS | PURCELL ROBERT H | 1985-12-05 | — | — | WO | claimed |
| US-4397839-A | RESPIRATORY DISTRESS SYNDROME | TOKYO TANABE COMPANY, LIMITED (JP) | 1983-08-09 | — | — | US | claimed |
| US-4338301-A | Lung tissue extract useful for treating hyaline-membrane disease and method for producing the extract | TOKYO TANABE CO., LTD. (JP) | 1982-07-06 | — | — | US | claimed |
| US-4279898-A | In vivo inhibitors of cholesterol biosynthesis | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 1981-07-21 | — | — | US | claimed |
| US-4152423-A | NONTOXIC, WATER SOLUBLE EXTRACTS OF MYCOBACTERIA OR NOCARDIA | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1979-05-01 | — | — | US | claimed |
| US-4127446-A | CULTIVATION OF STREPTOMYCES LAVENDULAE | ARAI TADASHI | 1978-11-28 | — | — | US | claimed |
| US-4032632-A | MIXTURE OF ANTIBIOTICS PRODUCED BY NEW SPECIES OF STREPTOSPORANGIUM | PFIZER INC. (US) | 1977-06-28 | — | — | US | claimed |