Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | GABRE | P78334 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10365280 | 0.99 | CNR2 (0.44) | CNR2SMN1; SMN2HSD17B10GABRPGABRD | |
| SCHEMBL10907133 | 0.85 | ALDH1A1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10366466 | 0.84 | CNR2 (0.46) | CNR2SMN1; SMN2HSD17B10KMT2AMEN1 | |
| Bromide SCHEMBL10365171 | 0.84 | ALDH1A1 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10909585 | 0.81 | MEN1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10365843 | 0.80 | CNR2 (0.40) | CNR2SMN1; SMN2KMT2AMEN1RAB9A | |
| Fumaric Acid SCHEMBL10366170 | 0.76 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10367833 | 0.75 | CNR2 (0.41) | CNR2SMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL10367832 | 0.75 | CNR2 (0.43) | CNR2SMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL10365419 | 0.73 | CNR2 (0.44) | CNR2SMN1; SMN2HSD17B10GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588727-A | ANALGESICS, TRANQUILLIZERS, ANTICONVULSANTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-05-13 | — | — | US | claimed |