Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | PKLR | P30613 | 5/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 6/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907799 | 0.90 | BCL2 (0.43) | BCL2MCL1PKLRPGAM1PTPN1 | |
| SCHEMBL497017 | 0.83 | MAPT (0.40) | BCL2MCL1PKLRPGAM1PTPN1 | |
| SCHEMBL10789834 | 0.83 | MAPT (0.40) | BCL2MCL1PKLRPGAM1PTPN1 | |
| SCHEMBL10984887 | 0.76 | ELANE (0.49) | MAPTELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL10633412 | 0.75 | BCL2 (0.41) | BCL2MCL1PKLRPGAM1PTPN1 | |
| SCHEMBL10584436 | 0.74 | BCL2 (0.48) | BCL2MCL1PKLRPGAM1PTPN1 | |
| SCHEMBL11424649 | 0.73 | MAOA (0.46) | MAPTELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL13083614 | 0.73 | PKLR (0.39) | BCL2MCL1PKLRSMN1; SMN2AKR1B1 | |
| SCHEMBL20218226 | 0.71 | ADORA2A (0.41) | MCL1MAPTELANEMEN1KMT2A | |
| SCHEMBL27321737 | 0.71 | MEN1 (0.42) | BCL2MCL1PKLRPGAM1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600537-A | ANTITUMOR AGENTS, CARBONYLATION | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-07-15 | — | — | US | disclosed |
| US-4465671-A | ANTI-LEUKEMIA AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-08-14 | — | — | US | disclosed |