Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.66 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320542 | 0.88 | NOTUM (0.54) | NOTUMPDK2P4HB | |
| SCHEMBL3903631 | 0.88 | EGFR (0.57) | NOTUMPDK2P4HBMEN1KMT2A | |
| SCHEMBL1997248 | 0.87 | NOTUM (0.73) | NOTUMPDK2CA1CA2CA12 | |
| SCHEMBL2772008 | 0.87 | NOTUM (0.52) | NOTUMPDK2CA1CA2CA12 | |
| SCHEMBL536675 | 0.86 | NOTUM (0.51) | NOTUMPDK2P4HBKDM4EALDH1A1 | |
| SCHEMBL15920972 | 0.85 | KDM4E (0.55) | NOTUMPDK2CA1CA2KDM4E | |
| SCHEMBL321308 | 0.84 | NOTUM (0.79) | NOTUMPDK2CA1CA2CA12 | |
| SCHEMBL10861732 | 0.84 | NOTUM (0.64) | NOTUMPDK2CA1CA2CA12 | |
| SCHEMBL14012580 | 0.84 | NOTUM (0.64) | NOTUMPDK2CA1CA2CA12 | |
| SCHEMBL2772563 | 0.84 | NOTUM (0.64) | NOTUMPDK2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628125-A | POLYESTERS, FILMS, FIBERS | POLAROID CORPORATION, PATENT DEPT. (US) | 1986-12-09 | — | — | US | disclosed |
| US-4433132-A | MOLECULAT ORIENTATED FILMS AND FIBERS | POLAROID CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |