Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 3/20 | 0.66 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 3/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.62 |
| ▸ | XDH | P47989 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399738 | 1.00 | P4HB (0.66) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL20820493 | 0.88 | CA12 (0.61) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL3902096 | 0.86 | NOTUM (0.69) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL1997248 | 0.86 | NOTUM (0.73) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL2310374 | 0.84 | CA12 (0.65) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL10907300 | 0.84 | NOTUM (0.66) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL30882491 | 0.84 | CA12 (0.56) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL30882564 | 0.84 | CA12 (0.56) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL10861732 | 0.83 | NOTUM (0.64) | P4HBNOTUMCA12CA1CA2 | |
| SCHEMBL321308 | 0.83 | NOTUM (0.79) | P4HBNOTUMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |