Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.86 |
| ▸ | AR | P10275 | 4/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.86 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.86 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.86 |
| ▸ | NR3C1 | P04150 | 11/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.79 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326217 | 1.00 | PGR (0.86) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL8199253 | 1.00 | PGR (0.86) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL8199259 | 1.00 | PGR (0.86) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL20223509 | 0.95 | PGR (0.89) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL6859132 | 0.94 | PGR (0.76) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11121922 | 0.93 | NR3C1 (0.75) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11881537 | 0.93 | NR3C1 (0.75) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL5501195 | 0.93 | NR3C1 (0.75) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11121923 | 0.93 | NR3C1 (0.75) | PGRARADORA3CHRM1ADRA1A | |
| Halobetasol Propionate SCHEMBL17190306 | 0.93 | PGR (1.00) | PGRARADORA3CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619921-A | Polyhalogeno-steroids | CIBA-GEIGY CORPORATION (US) | 1986-10-28 | — | — | US | disclosed |