Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861681 | 1.00 | KCNH3 (0.38) | KCNH3KMT2ATSHRSLC29A1CDK1 | |
| SCHEMBL10910185 | 0.99 | KMT2A (0.40) | KCNH3KMT2ATSHRSLC29A1CDK1 | |
| SCHEMBL11101380 | 0.94 | KMT2A (0.43) | KCNH3KMT2ATSHRSLC29A1CDK1 | |
| SCHEMBL11168811 | 0.93 | TSHR (0.36) | KCNH3KMT2ATSHRKDM4EGAA | |
| SCHEMBL9367808 | 0.91 | TSHR (0.36) | KCNH3KMT2ATSHRKDM4EGAA | |
| SCHEMBL10813615 | 0.89 | KMT2A (0.34) | KCNH3KMT2ATSHRSLC29A1CA1 | |
| SCHEMBL9249642 | 0.89 | TSHR (0.36) | KMT2ATSHRGAA | |
| SCHEMBL9524836 | 0.88 | TSHR (0.35) | KCNH3KMT2ATSHR | |
| SCHEMBL11250098 | 0.86 | TSHR (0.33) | TSHR | |
| SCHEMBL711949 | 0.86 | KMT2A (0.43) | KMT2ATSHRMEN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064752-B1 | PHOSPHAZENES SUBSTITUTED BY PIPERIDYL GROUPS, PROCESS FOR PREPARING THEM, THEIR USE AS STABILIZERS AND POLYMER COMPOSITIONS STABILIZED BY THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-08 | — | — | EP | disclosed |
| US-4451400-A | Phosphazenes useful as stabilizers in polymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
| EP-0064752-A2 | Phosphazenes substituted by piperidyl groups, process for preparing them, their use as stabilizers and polymer compositions stabilized by them | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-17 | — | — | EP | disclosed |