SCHEMBL10907340

SCHEMBL10907340

Cc1cccc(C(C)C)c1N1C(=O)c2ccc(O)cc2C1=O

nearest known ligand 0.84

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 6/20 0.84
DPP4 P27487 6/20 0.84
ESR1 P03372 7/20 0.54
ESR2 Q92731 4/20 0.54
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173289 0.92 ANPEP (1.00) ANPEPDPP4ESR1ESR2NR1H2
SCHEMBL29379602 0.84 DPP4 (0.65) ANPEPDPP4NR1H2NR1H3
SCHEMBL13171786 0.79 ANPEP (0.71) ANPEPDPP4NR1H2NR1H3
SCHEMBL22334750 0.77 DPP4 (0.53) ANPEPDPP4NR1H2NR1H3
SCHEMBL9588813 0.76 ANPEP (0.79) ANPEPDPP4ESR1ESR2
SCHEMBL9812636 0.74 ANPEP (0.69) ANPEPDPP4NR1H2NR1H3
SCHEMBL2818285 0.74 ANPEP (1.00) ANPEPDPP4NR1H2NR1H3
SCHEMBL29366407 0.74 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3
SCHEMBL2820118 0.74 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3
SCHEMBL29936544 0.74 ANPEP (0.68) ANPEPDPP4NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61171468-A None JP disclosed
JP-S61171468-A ISOINDOLINE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING SAME SANKYO CO LTD 1986-08-02 JP disclosed