SCHEMBL29379602

SCHEMBL29379602

Cc1cccc(C(C)C)c1N1C(=O)c2ccccc2C1=O

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.65
NR1H2 P55055 2/20 0.65
NR1H3 Q13133 2/20 0.65
ANPEP P15144 5/20 0.57
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 2/20 0.45
POLB P06746 1/20 0.45
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366407 0.90 DPP4 (0.78) DPP4NR1H2NR1H3ANPEPKMT2A
SCHEMBL2820118 0.90 DPP4 (0.78) DPP4NR1H2NR1H3ANPEPKMT2A
SCHEMBL10907340 0.84 ANPEP (0.84) DPP4NR1H2NR1H3ANPEP
SCHEMBL11016604 0.84 DPP4 (0.71) DPP4NR1H2NR1H3ANPEP
SCHEMBL10491139 0.84 DPP4 (0.68) DPP4NR1H2NR1H3ANPEPMEN1
SCHEMBL22334750 0.82 DPP4 (0.53) DPP4NR1H2NR1H3ANPEPMEN1
SCHEMBL11020887 0.82 DPP4 (0.56) DPP4NR1H2NR1H3ANPEP
SCHEMBL11018434 0.81 DPP4 (0.55) DPP4NR1H2NR1H3ANPEP
SCHEMBL11017462 0.81 DPP4 (0.59) DPP4NR1H2NR1H3ANPEP
SCHEMBL11022208 0.81 DPP4 (0.59) DPP4NR1H2NR1H3ANPEPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11513132-B2 Solid phase extraction, derivatization with crown ethers, and mass spectrometry, methods, reagents and kits TECAN SP, INC. (US) 2022-11-29 US disclosed
US-11465404-B2 On-press processing of a UV or violet-sensitized lithographic printing plate AGFA OFFSET BV (BE) 2022-10-11 US disclosed
US-11345766-B2 Tetrahydro-as-indacenyl catalyst composition, catalyst system, and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-05-31 US disclosed
EP-3452520-B1 TETRAHYDRO-AS-INDACENYL CATALYST COMPOSITION, CATALYST SYSTEM, AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-05-18 EP disclosed
US-20220032602-A1 ON-PRESS PROCESSING OF A UV OR VIOLET-SENSITIZED LITHOGRAPHIC PRINTING PLATE ECO3 BV (BE) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345766-B2 Tetrahydro-as-indacenyl catalyst composition, catalyst system, and processes for use thereof MLX, TXN, TSNAX DPP4 3312/4885NR1H2 1266/4885NR1H3 1653/4885
US-11513132-B2 Solid phase extraction, derivatization with crown ethers, and mass spectrometry, methods, reagents and kits CYP2C8, CES2, UGT1A8 DPP4 114/4885NR1H2 583/4885NR1H3 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.