SCHEMBL2818285

SCHEMBL2818285

CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccc(N)cc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 7/20 1.00
DPP4 P27487 7/20 0.69
NR1H2 P55055 1/20 0.56
NR1H3 Q13133 1/20 0.56
NPC1 O15118 4/20 0.53
ALDH1A1 P00352 4/20 0.53
RAB9A P51151 4/20 0.53
TSHR P16473 3/20 0.53
CASP1 P29466 3/20 0.53
CASP7 P55210 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MAPK1 P28482 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.42
CYP3A4 P08684 2/20 0.42
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PTPRC P08575 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13171786 0.83 ANPEP (0.71) ANPEPDPP4NR1H2NR1H3NPC1
SCHEMBL29366407 0.82 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3TSHR
SCHEMBL2820118 0.82 DPP4 (0.78) ANPEPDPP4NR1H2NR1H3TSHR
SCHEMBL9812636 0.82 ANPEP (0.69) ANPEPDPP4NR1H2NR1H3
SCHEMBL173289 0.82 ANPEP (1.00) ANPEPDPP4NR1H2NR1H3
SCHEMBL29566034 0.81 ANPEP (0.68) ANPEPDPP4NR1H2NR1H3
SCHEMBL17531021 0.80 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3NPC1
SCHEMBL30954668 0.80 ANPEP (0.67) ANPEPDPP4NR1H2NR1H3NPC1
SCHEMBL4151437 0.80 ANPEP (1.00) ANPEPDPP4NPC1ALDH1A1RAB9A
SCHEMBL6925321 0.80 ANPEP (0.66) ANPEPDPP4NR1H2NR1H3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4024128-B1 ELECTRONIC DEVICE AND ACCESSORY CANON KK (JP) 2026-05-20 EP claimed
CN-117415268-B Method for preparing high-toughness TC11 titanium alloy thick forging plate based on quasi-beta forging 西部超导材料科技股份有限公司 2026-05-15 CN claimed
EP-4080871-B1 ELECTRONIC APPARATUS AND ITS CONTROL METHOD, AND ACCESSORY AND ITS CONTROL METHOD CANON KK (JP) 2026-03-25 EP claimed
CN-121575269-A TC11 titanium alloy manufactured by high-temperature high-strength high-plasticity LMD additive and preparation method thereof 海南大学 2026-02-27 CN claimed
EP-4134739-B1 ELECTRONIC DEVICE, AND ACCESSORY CANON KK (JP) 2026-02-11 EP claimed
CN-120193191-A Preparation method of high-strength and high-toughness titanium alloy framework reinforced magnesium-based composite material 广东省科学院新材料研究所 2025-06-24 CN claimed
CN-117070086-B Protective heat-insulating paint capable of being coated on red and hot metal and application thereof 北京天力创玻璃科技开发有限公司 2025-06-17 CN claimed
CN-120133691-A Back pipe welding method for rotary target material 先导薄膜材料(安徽)有限公司 2025-06-13 CN claimed
CN-120079720-A Technological method for preparing TC11 high-strength titanium alloy seamless pipe 西部金属材料股份有限公司 2025-06-03 CN claimed
CN-115327332-B Test system and test method for power semiconductor device 青岛海宜丰电力电子有限公司 2025-05-27 CN claimed
CN-114310183-A Processing method of axial extrusion type pipe joint 沈阳航空航天大学 2022-04-12 CN claimed
CN-112756769-B Titanium alloy friction welding joint optimization method based on thermal coupling condition 西安理工大学 2022-04-12 CN claimed
CN-113481448-B Titanium alloy member and heat treatment method for titanium alloy member 北京航空航天大学 2022-03-08 CN claimed
CN-112097818-B Bionic impact-resistant sensor packaging structure and manufacturing method thereof 中北大学 2022-03-08 CN claimed
CN-114115261-A Time-adjustable robot tracking sliding mode control method 集美大学 2022-03-01 CN claimed
CN-113074126-B Two-stage axial flow compressor 上海尚实能源科技有限公司 2022-02-22 CN claimed
CN-114042917-A Preparation method of micron-sized titanium alloy product 湖南英捷高科技有限责任公司 2022-02-15 CN claimed
CN-114029489-A Method for improving plasticity of powder metallurgy titanium alloy 湖南英捷高科技有限责任公司 2022-02-11 CN claimed
WO-2008154353-A1 THALIDOMIDE ANALOGS FOR TREATING VASCULAR ABNORMALITIES CHARLESSON, LLC (US) 2008-12-18 WO claimed
US-20080306134-A1 THALIDOMIDE ANALOGS FOR TREATING VASCULAR ABNORMALITIES CHARLESSON, LLC 2008-12-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306134-A1 THALIDOMIDE ANALOGS FOR TREATING VASCULAR ABNORMALITIES VEGFA, FLT1, VCAM1 ANPEP 3507/4885DPP4 4355/4885NR1H2 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.