Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419400 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL10906457 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL7435532 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL5916364 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL13259166 | 0.81 | MEN1 (0.48) | ALDH1A1MMP8PIN1NPSR1LMNA | |
| SCHEMBL17460412 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL3963660 | 0.79 | MEN1 (0.44) | ALDH1A1MMP8RECQLPIN1NPSR1 | |
| SCHEMBL18065684 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL1522684 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MMP8RECQLPIN1POLB | |
| SCHEMBL5661041 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MMP8RECQLPIN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602006-A | Ynenolactone protease inhibitors | SYNTEX (U.S.A.) INC. (US) | 1986-07-22 | — | — | US | disclosed |