SCHEMBL7435532

SCHEMBL7435532

CCOC(=O)C(Cc1ccccc1)(Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
RECQL P46063 1/20 0.59
MMP8 P22894 1/20 0.59
PIN1 Q13526 1/20 0.50
PTPN1 P18031 5/20 0.47
POLB P06746 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
HIF1A Q16665 1/20 0.46
PTPRC P08575 1/20 0.46
PPID Q08752 1/20 0.45
PTPN2 P17706 1/20 0.44
PTPRA P18433 1/20 0.44
PTPRB P23467 1/20 0.44
LMNA P02545 3/20 0.43
TAAR1 Q96RJ0 2/20 0.43
TSHR P16473 1/20 0.43
THRB P10828 1/20 0.43
MAPT P10636 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17460412 0.93 ALDH1A1 (0.56) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL4419400 0.93 ALDH1A1 (0.62) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL29256551 0.91 ALDH1A1 (0.54) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL20350502 0.89 ALDH1A1 (0.52) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL5916364 0.88 ALDH1A1 (0.57) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL7057410 0.87 ALDH1A1 (0.48) ALDH1A1RECQLMMP8SMN1; SMN2HIF1A
SCHEMBL20347156 0.87 MMP8 (0.53) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL1522684 0.85 ALDH1A1 (0.58) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL18065684 0.85 ALDH1A1 (0.55) ALDH1A1RECQLMMP8PIN1PTPN1
SCHEMBL5661041 0.85 ALDH1A1 (0.55) ALDH1A1RECQLMMP8PIN1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102791674-A Compound having trimethylene structure, polymer compound containing unit that has trimethylene structure, and reactive compound having trimethylene structure HITACHI CHEMICAL CO LTD 2012-11-21 CN disclosed
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed