Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335555 | 0.93 | PRMT1 (0.54) | CASP6CTDSP1NT5EPRMT1MEN1 | |
| SCHEMBL10909529 | 0.92 | KMT2A (0.46) | CASP6CTDSP1NT5EPRMT1MEN1 | |
| SCHEMBL10907702 | 0.87 | CASP6 (0.55) | CASP6CTDSP1NT5EPRMT1HSD17B10 | |
| SCHEMBL11343753 | 0.85 | KMT2A (0.53) | PRMT1MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL11433382 | 0.85 | CASP6 (0.50) | CASP6CTDSP1NT5EPRMT1HSD17B10 | |
| SCHEMBL10905175 | 0.85 | NT5E (0.52) | CASP6CTDSP1NT5EPRMT1MEN1 | |
| SCHEMBL10907660 | 0.84 | CASP6 (0.60) | CASP6CTDSP1NT5EPRMT1MEN1 | |
| SCHEMBL10907788 | 0.84 | NT5E (0.62) | CASP6CTDSP1NT5EPRMT1MEN1 | |
| SCHEMBL10907950 | 0.84 | MEN1 (0.47) | CASP6PRMT1MEN1KMT2AHSD17B10 | |
| SCHEMBL10909338 | 0.83 | CASP6 (0.67) | CASP6CTDSP1NT5EPRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |