Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909338 | 0.94 | CASP6 (0.67) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL11344557 | 0.93 | PRMT1 (0.67) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL10905175 | 0.92 | NT5E (0.52) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL11422759 | 0.87 | PRMT1 (0.76) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL10905524 | 0.87 | CASP6 (0.70) | CASP6CTDSP1PRMT1SIRT1APEX1 | |
| SCHEMBL11425329 | 0.86 | CASP6 (0.66) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL10907788 | 0.86 | NT5E (0.62) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL11340696 | 0.85 | TIMP3 (0.56) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL10907618 | 0.84 | CASP6 (0.47) | CASP6CTDSP1PRMT1MAOAMAOB | |
| SCHEMBL10905184 | 0.84 | KMT2A (0.47) | CASP6CTDSP1PRMT1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |