Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694357 | 0.90 | KMT2A (0.55) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL1252918 | 0.82 | KMT2A (0.64) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL7306219 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL16443764 | 0.80 | KMT2A (0.48) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL19031434 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL1352270 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL4657892 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL3827192 | 0.79 | MAPK1 (0.51) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28991006 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL29649222 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590211-A | USING HYDROXYUREA PRODURG FOR SKIN DISORDERS | THE UPJOHN COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4302457-A | ACTIVATION OF PRO-DRUGS BY ULTRAVIOLET RADIATION IN TREATMENT OF SKIN DISORDERS | THE UPJOHN COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-4302456-A | UV RADIATION ACTIVATION OF PRO-DRUG, FOR SKIN DISEASE | THE UPJOHN COMPANY (US) | 1981-11-24 | — | — | US | disclosed |
| US-4235887-A | ADMINISTERING PRO-DRUG STEROID FOR SKIN DISORDERS | THE UPJOHN COMPANY (US) | 1980-11-25 | — | — | US | disclosed |