Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907705 | 0.86 | KMT2A (0.36) | ALDH1A1KDM4EPOLBTSHRAPOBEC3A | |
| SCHEMBL10905803 | 0.83 | CYP3A4 (0.36) | ALDH1A1HPGDKDM4EPOLBTSHR | |
| SCHEMBL10905442 | 0.83 | NQO1 (0.31) | — | |
| SCHEMBL10905662 | 0.83 | GAA (0.33) | ALDH1A1HPGDPOLBTSHRCYP3A4 | |
| SCHEMBL10906382 | 0.82 | POLB (0.42) | ALDH1A1KDM4EPOLBHTTMAPT | |
| Hydrochloric Acid SCHEMBL10906467 | 0.82 | KMT2A (0.32) | ALDH1A1HPGDTSHRCYP3A4MEN1 | |
| SCHEMBL10906378 | 0.81 | TSHR (0.43) | ALDH1A1HPGDKDM4ETSHRHTT | |
| SCHEMBL10903777 | 0.80 | SLC6A2 (0.31) | — | |
| SCHEMBL10907525 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EPOLBTSHR | |
| SCHEMBL10907869 | 0.79 | CYP3A4 (0.43) | HPGDKDM4EPOLBTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4562209-A | Promotion of feed efficiency in animals | WILLIAM H. RORER, INC. (US) | 1985-12-31 | — | — | US | disclosed |