Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907684 | 0.86 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10906692 | 0.85 | MEN1 (0.39) | KMT2AMEN1ALDH1A1KDM4EESR1 | |
| SCHEMBL10906409 | 0.84 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL10907913 | 0.84 | TSHR (0.42) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10903886 | 0.84 | LMNA (0.36) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10907009 | 0.83 | POLB (0.40) | KMT2AMEN1ESR1PGRADORA3 | |
| SCHEMBL10907002 | 0.81 | SCN9A (0.31) | SLC6A2SLC6A4 | |
| SCHEMBL10905771 | 0.81 | GRIN2D (0.38) | KMT2AMEN1KDM4EPTGS1SMN1; SMN2 | |
| SCHEMBL10906685 | 0.80 | — | — | |
| SCHEMBL10905773 | 0.78 | PTPN1 (0.42) | KMT2AKDM4ESMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |