Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 6/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5441358 | 0.87 | IAPP (0.53) | IAPPGABRA1GABRB2CA1 | |
| SCHEMBL23507040 | 0.83 | TAAR1 (0.50) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2050223 | 0.81 | HSP90AA1 (0.47) | HSP90AA1EGFRERBB2GABRA1GABRB2 | |
| SCHEMBL10908523 | 0.81 | IAPP (0.68) | IAPPEGFRGABRA1GABRB2CA1 | |
| SCHEMBL10908033 | 0.80 | IAPP (0.47) | IAPPEGFRERBB2GABRA1GABRB2 | |
| SCHEMBL1552241 | 0.77 | HSP90AA1 (0.50) | IAPPHSP90AA1EGFRERBB2GABRA1 | |
| SCHEMBL11077986 | 0.77 | HSP90AA1 (0.53) | IAPPHSP90AA1EGFRERBB2GABRA1 | |
| SCHEMBL29226127 | 0.76 | ALDH1A1 (0.40) | IAPPTAAR1 | |
| SCHEMBL29079403 | 0.75 | HSP90AA1 (0.52) | IAPPHSP90AA1EGFRERBB2GABRA1 | |
| SCHEMBL15319159 | 0.75 | HSP90AA1 (0.52) | IAPPHSP90AA1EGFRERBB2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594460-A | Process for selective C-alkylation of phenols | RHONE-POULENC SANTE (FR) | 1986-06-10 | — | — | US | disclosed |