Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061615 | 0.86 | GABRA1 (0.52) | EGFRGABRA1GABRB2CA1TAAR1 | |
| SCHEMBL13689952 | 0.82 | PKM (0.53) | TAAR1PNMTSHBGPKMHTR3E | |
| SCHEMBL10907778 | 0.81 | IAPP (0.46) | HSP90AA1EGFRERBB2GABRA1GABRB2 | |
| SCHEMBL1258491 | 0.80 | GABRA1 (0.52) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL8389267 | 0.80 | IAPP (0.52) | EGFRGABRA1GABRB2CA1TAAR1 | |
| SCHEMBL5785094 | 0.78 | ALDH1A1 (0.50) | EGFRERBB2GABRA1GABRB2CA1 | |
| SCHEMBL20906311 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2PKMALOX12TSHR | |
| SCHEMBL19510859 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2TAAR1 | |
| SCHEMBL19030702 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL10735838 | 0.77 | EGFR (0.39) | EGFRERBB2GABRA1GABRB2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1543455-B | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | SANKYO AGRO CO LTD | 2012-07-11 | — | — | CN | disclosed |
| US-7964531-B2 | 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7608563-B2 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | MITSUI AGRO CHEMICALS, INC. (JP) | 2009-10-27 | — | — | US | disclosed |
| EP-1426365-B9 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | MITSUI CHEMICALS AGRO INC (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-1426365-B1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | SANKYO AGRO CO LTD (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | SANKYO AGRO COMPANY, LIMITED (JP) | 2005-02-17 | — | — | US | disclosed |
| CN-1543455-A | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | 三共农业株式会社 | 2004-11-03 | — | — | CN | disclosed |
| EP-1426365-A1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | Sankyo Agro Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-4647677-A | Process for preparing 2,3-dihydro-7-aminobenzofurans | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4594438-A | Dehydrohalogenation heating of 2,2,6-tri-halo-6-(1-halisobutyl)cyclohexanone | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0090976-B1 | 2,2-DIHALO-6-HALO-6(1-HALOISOBUTYL)CYCLOHEXANONE | MITSUBISHI KASEI CORPORATION (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4499306-A | HALOGENATION OF 2-ISOBUTYLIDENE CYCLOHEXANONE IN PRESENCE OF CATALST | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0090976-A2 | 2,2-Dihalo-6-halo-6(1-haloisobutyl)cyclohexanone | MITSUBISHI KASEI CORPORATION (JP) | 1983-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | CBR3, DDT, CBR1 | HSP90AA1 2317/4885EGFR 2338/4885ERBB2 451/4885 |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | CBR3, DDT, CHRM2 | HSP90AA1 2576/4885EGFR 1380/4885ERBB2 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.