Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338954 | 0.94 | APEX1 (0.49) | APEX1BRAFPRMT1MAOBMEN1 | |
| SCHEMBL10905228 | 0.92 | APEX1 (0.49) | APEX1BRAFPRMT1MAOBMEN1 | |
| SCHEMBL11350863 | 0.85 | PRMT1 (0.51) | APEX1BRAFPRMT1MAOBMEN1 | |
| SCHEMBL11512326 | 0.85 | TIMP3 (0.45) | APEX1BRAFPRMT1MEN1KMT2A | |
| SCHEMBL10909636 | 0.84 | BRAF (0.41) | APEX1BRAFPRMT1MEN1KMT2A | |
| SCHEMBL11588083 | 0.84 | APEX1 (0.58) | APEX1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL10907569 | 0.84 | APEX1 (0.63) | APEX1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL10907842 | 0.83 | APEX1 (0.62) | APEX1PRMT1MAOBMEN1KMT2A | |
| SCHEMBL10907786 | 0.80 | NT5E (0.44) | APEX1PRMT1MAOBMEN1KMT2A | |
| SCHEMBL10907645 | 0.80 | CD40 (0.43) | BRAFPRMT1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |