Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417274 | 0.94 | PRMT1 (0.49) | NT5EPRMT1ENPP2MAPTTRPV1 | |
| SCHEMBL10908562 | 0.92 | PRMT1 (0.46) | NT5EPRMT1ENPP2LMNAMAPT | |
| SCHEMBL11346336 | 0.85 | PRMT1 (0.55) | NT5EPRMT1ENPP2MAPTCASP6 | |
| SCHEMBL10908622 | 0.85 | ENPP2 (0.43) | NT5EENPP2LMNAMAPTPOLB | |
| SCHEMBL11512326 | 0.84 | TIMP3 (0.45) | NT5EPRMT1ENPP2LMNAMAPT | |
| SCHEMBL10909518 | 0.84 | NT5E (0.61) | NT5EPRMT1ENPP2LMNAMAPT | |
| SCHEMBL10905209 | 0.83 | ENPP2 (0.51) | NT5EPRMT1ENPP2CASP6CTDSP1 | |
| SCHEMBL10908090 | 0.83 | PRMT1 (0.46) | NT5EPRMT1ENPP2LMNAMAPT | |
| SCHEMBL10907727 | 0.83 | ENPP2 (0.45) | NT5EPRMT1ENPP2LMNACASP6 | |
| SCHEMBL10907835 | 0.82 | MAOB (0.40) | PRMT1LMNAMAPTPOLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |