Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354729 | 0.94 | PRMT1 (0.44) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL10905168 | 0.91 | MEN1 (0.46) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL11435673 | 0.87 | CASP6 (0.48) | CASP6CTDSP1L3MBTL1APEX1MEN1 | |
| SCHEMBL10907696 | 0.86 | CASP6 (0.44) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL10907966 | 0.85 | CASP6 (0.56) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL11426327 | 0.85 | CASP6 (0.48) | CASP6CTDSP1APEX1MEN1MAPT | |
| SCHEMBL11354660 | 0.85 | MEN1 (0.46) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL11423148 | 0.84 | POLB (0.51) | L3MBTL1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL10907672 | 0.83 | CASP6 (0.65) | CASP6CTDSP1APEX1MEN1MAPT | |
| SCHEMBL10909117 | 0.83 | MEN1 (0.46) | CASP6CTDSP1L3MBTL1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |