Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 4/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427527 | 0.91 | CASP6 (0.48) | CASP6CTDSP1APEX1PRMT1NSD2 | |
| SCHEMBL11435673 | 0.91 | CASP6 (0.48) | CASP6CTDSP1APEX1PRMT1MAOA | |
| SCHEMBL11436204 | 0.85 | CASP6 (0.65) | CASP6CTDSP1APEX1PRMT1NSD2 | |
| SCHEMBL11440636 | 0.85 | CASP6 (0.46) | CASP6CTDSP1APEX1PRMT1NSD2 | |
| SCHEMBL11354729 | 0.85 | PRMT1 (0.44) | CASP6CTDSP1APEX1PRMT1MAOA | |
| SCHEMBL10908373 | 0.85 | CASP6 (0.43) | CASP6CTDSP1APEX1PRMT1MAOA | |
| SCHEMBL11425994 | 0.84 | SMN1; SMN2 (0.56) | CTDSP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11428914 | 0.83 | CASP6 (0.64) | CASP6CTDSP1APEX1PRMT1MAOA | |
| SCHEMBL11433965 | 0.83 | CASP6 (0.48) | CASP6CTDSP1APEX1PRMT1NSD2 | |
| SCHEMBL11426646 | 0.83 | CASP6 (0.43) | CASP6CTDSP1APEX1PRMT1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |