Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342247 | 0.93 | MAPT (0.46) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11428018 | 0.87 | MEN1 (0.44) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11425953 | 0.84 | MEN1 (0.44) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10907481 | 0.84 | DEGS1 (0.45) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11423181 | 0.83 | POLB (0.51) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10907484 | 0.81 | ENPP2 (0.45) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10909166 | 0.81 | ENPP2 (0.43) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10909117 | 0.81 | MEN1 (0.46) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11422184 | 0.81 | SMN1; SMN2 (0.56) | RAB9AMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10907688 | 0.81 | KMT2A (0.46) | RAB9AMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |