Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343138 | 0.94 | HPSE (0.46) | ENPP2NPC1RAB9AHPSEDHODH | |
| SCHEMBL11427500 | 0.86 | ENPP2 (0.49) | ENPP2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10907826 | 0.85 | ENPP2 (0.51) | ENPP2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10907894 | 0.85 | ENPP2 (0.45) | ENPP2NPC1RAB9AHPSEDHODH | |
| SCHEMBL10905493 | 0.85 | NT5E (0.59) | ENPP2NPC1RAB9AHPSEMEN1 | |
| SCHEMBL10907548 | 0.83 | HPSE (0.47) | ENPP2HPSEMEN1KMT2ACASP6 | |
| SCHEMBL11435634 | 0.83 | ENPP2 (0.47) | ENPP2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10909132 | 0.83 | ENPP2 (0.50) | ENPP2NPC1RAB9AHPSEDHODH | |
| SCHEMBL11432085 | 0.82 | MEN1 (0.55) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL10907559 | 0.82 | KMT2A (0.47) | ENPP2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |