SCHEMBL10908511

SCHEMBL10908511

CCCC(=O)c1c(O)cc(O)c(C(=O)CCC)c1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.72
PLA2G2A P14555 2/20 0.72
PLA2G5 P39877 2/20 0.72
FASN P49327 2/20 0.62
ALDH1A1 P00352 2/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
RECQL P46063 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PAK1 Q13153 1/20 0.47
CYP3A4 P08684 1/20 0.47
PTGS1 P23219 1/20 0.47
DRD3 P35462 1/20 0.47
HSD17B3 P37058 1/20 0.45
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28920255 0.92 FFAR1 (0.62) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL10910461 0.89 FFAR1 (0.60) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL10908720 0.89 FFAR1 (0.60) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL20556365 0.88 FASN (0.69) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL9752830 0.88 PLA2G2A (0.86) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL9752583 0.86 PLA2G2A (0.96) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL10908716 0.85 FFAR1 (0.55) FFAR1PLA2G2APLA2G5FASNALDH1A1
SCHEMBL9752843 0.84 PLA2G2A (1.00) FFAR1PLA2G2APLA2G5ALDH1A1MEN1
SCHEMBL9752712 0.84 PLA2G2A (1.00) FFAR1PLA2G2APLA2G5ALDH1A1MEN1
Didodecanoylphloroglucinol SCHEMBL9188500 0.84 PLA2G2A (1.00) FFAR1PLA2G2APLA2G5ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069536-A1 Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds NORISTAN LIMITED (ZA) 1983-01-12 EP claimed
WO-2025104281-A1 HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-05-22 WO disclosed
EP-0069536-B1 PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS NORISTAN LIMITED (ZA) 1986-12-17 EP disclosed
US-4578520-A Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds NORISTAN LIMITED (ZA) 1986-03-25 US disclosed
US-4503256-A BACTERICIDES, FUNGICIDES NORISTAN LIMITED (ZA) 1985-03-05 US disclosed
EP-0069536-A1 Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds NORISTAN LIMITED (ZA) 1983-01-12 EP disclosed